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WDR48 and FANCI
Data Source:
BioGRID
(pull down)
WDR48
FANCI
Description
WD repeat domain 48
FA complementation group I
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Lysosome
Late Endosome
Intracellular Membrane-bounded Organelle
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Molecular Function
DNA Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Protein Binding
Ubiquitin Binding
DNA Binding
Protein Binding
DNA Polymerase Binding
Biological Process
Double-strand Break Repair Via Homologous Recombination
Cellular Response To DNA Damage Stimulus
Spermatogenesis
Single Fertilization
Viral Process
Protein Deubiquitination
Multicellular Organism Growth
Interstrand Cross-link Repair
DNA Damage Response, Detection Of DNA Damage
Skin Development
Embryonic Organ Development
Skeletal System Morphogenesis
Homeostasis Of Number Of Cells
Positive Regulation Of Epithelial Cell Proliferation
Seminiferous Tubule Development
Regulation Of Protein Monoubiquitination
Positive Regulation Of Protein Deubiquitination
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Cell Cycle
Positive Regulation Of Protein Ubiquitination
Interstrand Cross-link Repair
Pathways
Recognition of DNA damage by PCNA-containing replication complex
Ub-specific processing proteases
Fanconi Anemia Pathway
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
Fanconi Anemia Pathway
TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases
Fanconi anemia
GWAS
Metabolic syndrome (
31589552
)
Social communication problems (
24564958
)
Height (
25282103
)
Menopause (age at onset) (
26414677
)
Red cell distribution width (
32888494
)
Serum immune biomarker levels (
32066700
)
Interacting Genes
7 interacting genes:
FANCI
NMRAL1
PAXIP1
PCNA
PHLPP1
RAD51
UBC
13 interacting genes:
AKT1
APP
ATR
BRCA2
FANCD2
FANCL
MTDH
MTNR1B
PIAS1
RAD51
UBL5
USP1
WDR48
Entrez ID
57599
55215
HPRD ID
11146
13339
Ensembl ID
ENSG00000114742
ENSG00000140525
Uniprot IDs
A0A024R2L1
Q8TAF3
B3KNW8
Q9NVI1
PDB IDs
5CVL
5CVN
5CVO
5K1A
5K1B
5K1C
5L8E
5L8W
6JLQ
6VAA
6VAD
6VAE
6VAF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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