ZNF512B and AP1G1

Data Source:
BioGRID (two hybrid)

		ZNF512B	AP1G1
Description		zinc finger protein 512B	adaptor related protein complex 1 subunit gamma 1
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GO Annotations	Cellular Component	Nucleoplasm	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Membrane AP-1 Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Protein Binding Kinesin Binding GTP-dependent Protein Binding Small GTPase Binding Clathrin Adaptor Activity Cargo Adaptor Activity
	Biological Process		Intracellular Protein Transport Golgi To Vacuole Transport Receptor-mediated Endocytosis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Organization Endosome To Melanosome Transport Positive Regulation Of Natural Killer Cell Degranulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Defense Response To Virus By Virus Golgi To Lysosome Transport
Pathways			Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Birth weight ( 31043758) Mean platelet volume ( 32888494) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)	General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) Post bronchodilator FEV1 ( 26634245) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		71 interacting genes: AJUBA ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BANP BRD1 BTBD2 C11orf68 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 GOLGA2 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MDFI MEOX2 MTUS2 MYH10 NACC1 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RABEP1 RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2 ZNF143 ZYX	27 interacting genes: AAGAB AFTPH AP1AR AP1B1 AP1M2 AP1S1 AP1S2 ARF1 ARFRP1 BAALC CCDC91 CLINT1 CLTC DNER EPS15 HEATR5B KIF13A MAP1A PSEN2 RABEP1 RABGEF1 SNX9 SPTB SYNRG SYP UBL7 ZNF512B
Entrez ID		57473	164
HPRD ID		13840	04637
Ensembl ID		ENSG00000196700	ENSG00000166747
Uniprot IDs		Q96KM6	A0A140VJE7 O43747 Q8IY97
PDB IDs		2GQJ	1IU1
Enriched GO Terms of Interacting Partners?
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