ZNF512B and TOM1

Data Source:
BioGRID (two hybrid)

		ZNF512B	TOM1
Description		zinc finger protein 512B	target of myb1 membrane trafficking protein
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GO Annotations	Cellular Component	Nucleoplasm	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Protein Binding Clathrin Binding
	Biological Process		Intracellular Protein Transport Endocytosis Signal Transduction Protein Transport Endosomal Transport Neutrophil Degranulation
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Mean platelet volume ( 32888494) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)	Cholesterol, total ( 24097068) HDL cholesterol ( 29404214) High density lipoprotein cholesterol levels ( 31217584) Hippocampal volume in mild cognitive impairment ( 29274321) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Total cholesterol levels ( 28334899) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		71 interacting genes: AJUBA ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BANP BRD1 BTBD2 C11orf68 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 GOLGA2 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MDFI MEOX2 MTUS2 MYH10 NACC1 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RABEP1 RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2 ZNF143 ZYX	21 interacting genes: APP CLTC DAZAP2 EEA1 ILVBL LITAF LRRC20 MAP3K1 MYO6 NAA11 NEDD4 PILRA PTBP2 RPS27 SMURF1 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B
Entrez ID		57473	10043
HPRD ID		13840	05265
Ensembl ID		ENSG00000196700	ENSG00000100284
Uniprot IDs		Q96KM6	B3KUF5 O60784
PDB IDs		2GQJ	1ELK 1WRD 2N2N 2N9D 6J56
Enriched GO Terms of Interacting Partners?
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