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RAD18 and DAZAP2
Data Source:
BioGRID
(two hybrid)
RAD18
DAZAP2
Description
RAD18 E3 ubiquitin protein ligase
DAZ associated protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Replication Fork
Cytoplasm
Centrosome
Nuclear Body
Site Of Double-strand Break
Nuclear Inclusion Body
Rad6-Rad18 Complex
Cytoplasm
Nuclear Speck
Protein-containing Complex
Molecular Function
Y-form DNA Binding
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Protein-containing Complex Binding
Metal Ion Binding
Protein Binding
Receptor Tyrosine Kinase Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Identical Protein Binding
Protein Serine/threonine Kinase Activator Activity
WW Domain Binding
Biological Process
DNA Repair
Postreplication Repair
Protein Monoubiquitination
Cellular Response To DNA Damage Stimulus
Response To UV
Protein Ubiquitination
DNA Damage Response, Detection Of DNA Damage
Protein Autoubiquitination
Positive Regulation Of Chromosome Segregation
Negative Regulation Of Cell Death
Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Recognition of DNA damage by PCNA-containing replication complex
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Chronotype (
30696823
)
Clopidogrel active metabolite levels (
28207573
)
Metabolite levels (
23823483
)
Morning person (
30696823
)
Sleep duration (
30531941
)
Transverse temporal cortex volume (
31530798
)
Interacting Genes
30 interacting genes:
ARRDC3
DAZAP2
DZIP3
GOLGA2
MAGEA4
MAP3K1
MAPK8
MLKL
NBN
ORC2
PCGF6
PCNA
PDCD5
POLK
RAD51
RFC2
SHPRH
SIVA1
TAX1BP1
TP53BP1
TRIM23
TRIM8
TSG101
UBC
UBE2A
UBE2B
UBE2D2
UBE2I
USP2
USP7
164 interacting genes:
AATF
ACOT7
AOC1
ARID5A
ATXN1
ATXN1L
BAG3
BATF2
BHLHE40
C1orf94
CALCOCO2
CAMK2A
CAPN15
CCDC120
CDK4
CELF5
CEP70
CLASRP
COL4A2
COL4A5
CXCL12
DAB1
DAZ1
DAZL
DCUN1D1
DESI1
DTX2
EPN1
EPN2
EPN3
ESRP1
EXD3
FAM168A
FAM83A
FBN3
FOXH1
GGA3
GPS2
GPSM1
HEY1
HGS
HIP1
INCA1
KLHL42
KRTAP19-1
KRTAP19-3
KRTAP19-5
KRTAP19-7
KRTAP26-1
KRTAP6-1
KRTAP6-2
KRTAP8-1
LASP1
LGALS9
LITAF
LMO2
MAGED1
MAPK1IP1L
MED31
MINDY1
MINDY3
MTURN
MYEOV
MYOZ3
NDUFA5
NEDD4
NEDD4L
NOC4L
NOTCH1
OPTN
OTUB2
OTUD7B
OTULIN
PATZ1
PDIK1L
PEF1
PITX2
PLEKHB2
PLEKHF2
PLSCR1
PLSCR4
POGZ
POLI
PROP1
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR34
RABGEF1
RAD18
RAD23A
RAMAC
RBFOX1
RBFOX2
RBM11
RBM24
RBM43
RBPMS
RHOXF2
RNF115
RNF208
RNF44
ROR2
RPS27A
SEPTIN2
SMAP2
SMURF2
SNRPC
SOX10
SOX6
SQSTM1
STAM2
STAT6
TAX1BP1
TBX6
TCF7L2
TENT5B
TENT5C
TEX37
TFG
TIAL1
TLE1
TLE5
TNIP1
TNIP3
TOLLIP
TOM1
UBA52
UBAC1
UBAP2
UBASH3A
UBASH3B
UBB
UBC
UBE2D4
UBE2E2
UBE2E3
UBE2V1
UBE3A
UBQLN1
UBQLN2
UBQLN4
UBXN6
UBXN7
USP13
USP5
VENTX
VEZF1
VHLL
VPS37C
WDR73
WWOX
WWP1
YOD1
ZBTB32
ZC3H10
ZFAND2A
ZFAND2B
ZFYVE9
ZNF34
ZNF581
Entrez ID
56852
9802
HPRD ID
09242
08463
Ensembl ID
ENSG00000070950
ENSG00000183283
Uniprot IDs
Q9NS91
A0A024R110
Q15038
PDB IDs
2MRE
2MRF
2Y43
2YBF
5VF0
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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