PRKCSH and GET4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRKCSH	GET4
Description		protein kinase C substrate 80K-H	guided entry of tail-anchored proteins factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Glucosidase II Complex Intracellular Membrane-bounded Organelle	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol BAT3 Complex
	Molecular Function	Protein Kinase C Binding Calcium Ion Binding Protein Binding Ion Channel Binding Phosphoprotein Binding	Protein Binding Chaperone Binding
	Biological Process	Liver Development Protein Folding N-glycan Processing Intracellular Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process	Protein Insertion Into ER Membrane Cytoplasmic Sequestering Of Protein Tail-anchored Membrane Protein Insertion Into ER Membrane Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Advanced glycosylation endproduct receptor signaling Post-translational protein phosphorylation Calnexin/calreticulin cycle Maturation of spike protein Maturation of spike protein	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Polycystic liver disease
GWAS		Presence of antiphospholipid antibodies ( 27098658) Serum metabolite levels (CMS) ( 31636271)	PR interval ( 32439900)
Interacting Genes		10 interacting genes: ARL4D CANX ESR1 GANAB GBA3 GET4 PTPRC RGS2 RPS6 VDR	29 interacting genes: AKT1 ATP5PD BAG6 C1orf109 CAPNS1 CDKN1A CEP126 DUSP21 EEF1G ENKD1 FBN1 FLYWCH2 GET3 GIT2 KAT5 KIFC2 KRTAP9-3 NUP85 PLK1 PRKAB2 PRKCSH PTMS SDCBP SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2
Entrez ID		5589	51608
HPRD ID		03518	12909
Ensembl ID		ENSG00000130175	ENSG00000239857
Uniprot IDs		B4DJQ5 K7ELL7 P14314	Q7L5D6
PDB IDs			6AU8
Enriched GO Terms of Interacting Partners?
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