USE1 and APOL2

Data Source:
BioGRID (two hybrid)

		USE1	APOL2
Description		unconventional SNARE in the ER 1	apolipoprotein L2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane COPI-coated Vesicle SNARE Complex	Extracellular Region Endoplasmic Reticulum Membrane Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Lysosomal Transport Protein Transport Protein Catabolic Process Secretion By Cell Membrane Fusion	Lipid Metabolic Process Lipid Transport Acute-phase Response Multicellular Organism Development Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy
Pathways		COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Night sleep phenotypes ( 27126917)	Epigenetic age acceleration in alcohol use disorder ( 31466081)
Interacting Genes		18 interacting genes: APOL2 APP AQP6 BSCL2 CALN1 CCDC70 CCM2L CREB3 EBP JAGN1 LMNA MEOX2 MFSD14B SCN3B STX1A STX4 TMEM86B TRIM27	33 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 EMP1 FAM209A GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 STX1A STX2 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6
Entrez ID		55850	23780
HPRD ID		11299	06263
Ensembl ID		ENSG00000053501	ENSG00000128335
Uniprot IDs		Q9NZ43	A0A024R1M8 J3KQL8 Q9BQE5
PDB IDs
Enriched GO Terms of Interacting Partners?
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