KIF16B and GINS4

Data Source:
BioGRID (two hybrid)

		KIF16B	GINS4
Description		kinesin family member 16B	GINS complex subunit 4
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GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Spindle Cytosol Kinesin Complex Microtubule Early Endosome Membrane	GINS Complex Nucleoplasm Cytoplasm CMG Complex
	Molecular Function	Microtubule Motor Activity ATP Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding
	Biological Process	Formation Of Primary Germ Layer Regulation Of Receptor Recycling Golgi To Endosome Transport Microtubule-based Movement Epidermal Growth Factor Receptor Signaling Pathway Endoderm Development Fibroblast Growth Factor Receptor Signaling Pathway Receptor Catabolic Process Early Endosome To Late Endosome Transport	Double-strand Break Repair Via Break-induced Replication Inner Cell Mass Cell Proliferation DNA Strand Elongation Involved In DNA Replication
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Unwinding of DNA Unwinding of DNA
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Asthma ( 27611488) Body mass index ( 26426971) Chronotype ( 30696823) Dimensional psychopathology (Positive) ( 29496196) Emphysema imaging phenotypes ( 26030696) Gut microbiota alpha diversity (Chao1 index) ( 33208821) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota alpha diversity (Shannon index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) Ileal carcinoids ( 21139019) Intelligence ( 22449649) Lipid traits ( 30576415) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Sweet taste preference ( 32572145)
Interacting Genes		10 interacting genes: GABARAPL2 GINS4 IL16 ITSN1 LGALS3 PRKAA1 PRKAA2 SMYD1 TCEANC TSR2	17 interacting genes: BIN3 CDC45 CTNNBIP1 DMAP1 GINS1 GINS2 GINS3 KIF16B LHX8 MCM2 PBX4 POLA1 POLD1 POLE PPP1R13B SIK1 SIK1B
Entrez ID		55614	84296
HPRD ID		10731	11583
Ensembl ID		ENSG00000089177	ENSG00000147536
Uniprot IDs		A0A140VK74 A0A1B0GTU3 Q96L93	Q9BRT9
PDB IDs		2V14 6EE0	2E9X 2EHO 2Q9Q 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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