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OTUD5 and NONO
Data Source:
BioGRID
(pull down)
OTUD5
NONO
Description
OTU deubiquitinase 5
non-POU domain containing octamer binding
Image
GO Annotations
Cellular Component
Cytosol
Fibrillar Center
Nucleus
Nucleoplasm
Membrane
Nuclear Matrix
Nuclear Speck
Paraspeckles
RNA Polymerase II Transcription Regulator Complex
Molecular Function
Thiol-dependent Ubiquitin-specific Protease Activity
Cysteine-type Peptidase Activity
Lys63-specific Deubiquitinase Activity
Ubiquitinyl Hydrolase Activity
Lys48-specific Deubiquitinase Activity
Transcription Regulatory Region Sequence-specific DNA Binding
Nucleic Acid Binding
Chromatin Binding
RNA Binding
Protein Binding
Identical Protein Binding
Biological Process
Protein Deubiquitination
Protein Phosphopantetheinylation
Negative Regulation Of Type I Interferon Production
Response To Lipopolysaccharide
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
MRNA Splicing, Via Spliceosome
Activation Of Innate Immune Response
DNA Repair
DNA Recombination
Regulation Of Transcription, DNA-templated
MRNA Processing
Circadian Rhythm
RNA Splicing
Regulation Of Circadian Rhythm
Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways
Ovarian tumor domain proteases
Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS
Interacting Genes
12 interacting genes:
ARPC3
NEDD8
NONO
PDCD5
POLR2A
POLR2B
POLR2C
SUB1
TP53
TRAF3
UBC
UBR5
115 interacting genes:
APBB1
AR
BHLHE41
C11orf68
CA2
DDX6
DELEC1
ERCC6
ERG
ESR1
EWSR1
FXR2
H3-4
IL7R
IRAK3
LMO4
MAD1L1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYC
MYCN
ORC5
OTUD5
PIN1
PLEKHF2
POLR1H
POLR2A
PPP1CA
PPP1CB
PPP1CC
PRKAA2
PRPF40A
PSPC1
PTBP1
SFPQ
SMARCB1
SMARCC1
SMARCD1
SPI1
SUMO2
SYNPO
TCERG1
UBE2D1
UBE2I
WBP4
Entrez ID
55593
4841
HPRD ID
06488
02098
Ensembl ID
ENSG00000068308
ENSG00000147140
Uniprot IDs
A0A024QZ09
Q96G74
A0A0S2Z4Z9
Q15233
PDB IDs
3PFY
3TMO
3TMP
3SDE
5IFM
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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