IMP3 and LPXN

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IMP3	LPXN
Description		IMP U3 small nucleolar ribonucleoprotein 3	leupaxin
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Preribosome Small-subunit Processome Mpp10 Complex	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding RRNA Binding SnoRNA Binding	Transcription Coregulator Activity Protein Binding Metal Ion Binding
	Biological Process	RRNA Processing	Regulation Of Transcription, DNA-templated Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Endothelial Cell Migration Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)
Interacting Genes		15 interacting genes: CCNDBP1 EFHC1 EVI5 KLC3 LPXN MCC MPHOSPH10 NANOS3 PPP1R12C SERTAD3 SORBS3 TFIP11 USHBP1 ZNF655 ZYX	33 interacting genes: AGXT AQP1 GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 LMO3 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RNF214 RUNX1T1 SFI1 TGFB1 TNS2 TXLNB VCL ZNF175 ZNF426
Entrez ID		55272	9404
HPRD ID		12664	05651
Ensembl ID		ENSG00000177971	ENSG00000110031
Uniprot IDs		Q9NV31	B7Z5P7 O60711
PDB IDs		2CQJ	1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?
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