IMP3 and EVI5

Data Source:
BioGRID (two hybrid)

		IMP3	EVI5
Description		IMP U3 small nucleolar ribonucleoprotein 3	ecotropic viral integration site 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Preribosome Small-subunit Processome Mpp10 Complex	Nucleus Microtubule Organizing Center Spindle Cytosol
	Molecular Function	RNA Binding Protein Binding RRNA Binding SnoRNA Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	RRNA Processing	Intracellular Protein Transport Cell Cycle Retrograde Transport, Endosome To Golgi Positive Regulation Of GTPase Activity Cell Division Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein B levels ( 32203549) Asthma or allergic disease (pleiotropy) ( 29785011) Cholesterol, total ( 24097068 25961943 20686565) Epstein Barr virus nuclear antigen 1 IgG levels or multiple sclerosis ( 26819262) LDL cholesterol ( 30275531 25961943) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244 24076602 19525955 21833088 27386562) Systemic lupus erythematosus ( 28714469) Total cholesterol levels ( 28334899 30275531)
Interacting Genes		15 interacting genes: CCNDBP1 EFHC1 EVI5 KLC3 LPXN MCC MPHOSPH10 NANOS3 PPP1R12C SERTAD3 SORBS3 TFIP11 USHBP1 ZNF655 ZYX	22 interacting genes: ARL4A AURKB BIRC5 CCDC185 CEP19 CSNK1D ELOA FAM161A FBXO5 IMP3 INCENP LENG1 LMO1 MB21D2 MCRS1 MORF4L2 PRPF31 REP15 STX3 TCEANC TNFAIP8L1 ZNF446
Entrez ID		55272	7813
HPRD ID		12664	04249
Ensembl ID		ENSG00000177971	ENSG00000067208
Uniprot IDs		Q9NV31	O60447 Q59FE7
PDB IDs		2CQJ
Enriched GO Terms of Interacting Partners?
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