BBS7 and PDE8B

Data Source:
BioGRID (biochemical)

		BBS7	PDE8B
Description		Bardet-Biedl syndrome 7	phosphodiesterase 8B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nucleus Centrosome Cytosol Axoneme Membrane BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Cellular_component Cytosol
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding
	Biological Process	Eye Development Heart Looping Regulation Of Transcription By RNA Polymerase II Smoothened Signaling Pathway Determination Of Left/right Symmetry Brain Development Visual Perception Protein Localization Protein Transport Melanosome Transport Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Fat Cell Differentiation Intracellular Transport Digestive Tract Morphogenesis Pigment Granule Aggregation In Cell Center Limb Development Cilium Assembly Primary Palate Development Non-motile Cilium Assembly	CAMP Catabolic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		BBSome-mediated cargo-targeting to cilium	G alpha (s) signalling events
Drugs			Caffeine Trapidil
Diseases		Bardet-Biedl syndrome (BBS)	Pigmented micronodular adrenocortical disease (PPNAD)
GWAS		Asthma ( 31959851)	Autoimmune thyroid disease ( 32581359) Caudate nucleus volume ( 21502949) Chronotype ( 30696823) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965 22493691) Medication use (thyroid preparations) ( 31015401) Serum thyroid-stimulating hormone levels ( 25436638) SjÃ¶gren's syndrome ( 28076899) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335 18514160)
Interacting Genes		4 interacting genes: FHOD1 JUN KRT18 PAX2
Entrez ID		55212	8622
HPRD ID		07399	04546
Ensembl ID		ENSG00000138686	ENSG00000113231
Uniprot IDs		Q8IWZ6	B3KN77 O95263
PDB IDs
Enriched GO Terms of Interacting Partners?
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