PDE8B

Description		phosphodiesterase 8B
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol
	Molecular Function	3',5'-cyclic-nucleotide Phosphodiesterase Activity 3',5'-cyclic-AMP Phosphodiesterase Activity Metal Ion Binding
	Biological Process	CAMP Catabolic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		G alpha (s) signalling events
Drugs		Caffeine Trapidil
Diseases		Pigmented micronodular adrenocortical disease (PPNAD)
GWAS		Autoimmune thyroid disease ( 32581359) Caudate nucleus volume ( 21502949) Chronotype ( 30696823) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965 22493691) Medication use (thyroid preparations) ( 31015401) Serum thyroid-stimulating hormone levels ( 25436638) SjÃ¶gren's syndrome ( 28076899) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335 18514160)
Novel Interacting Genes		2 novel interacting genes: BBS7 SSBP2
Interacting Genes
Entrez ID		8622
HPRD ID		04546
Ensembl ID		ENSG00000113231
Uniprot IDs		B3KN77 O95263
PDB IDs
Enriched GO Terms of Interacting Partners?
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