DPPA4 and INO80B

Data Source:
BioGRID (two hybrid)

		DPPA4	INO80B
Description		developmental pluripotency associated 4	INO80 complex subunit B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Nucleolus Ino80 Complex
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Multicellular Organism Development Somatic Stem Cell Population Maintenance System Development	DNA Repair DNA Recombination Protein Deubiquitination ATP-dependent Chromatin Remodeling
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)
Interacting Genes		35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM	64 interacting genes: ABI2 BANP BHLHB9 BOLL CARD9 CAVIN1 CCDC85B CD81 CDR2L CEP70 CSNK2B CYSRT1 DPPA4 DVL3 E2F6 FLACC1 GOLGA6L9 HMBOX1 HMGXB4 HOMEZ HOXA1 HSF2BP IGFBP2 KCTD7 KRT34 KRT40 KRTAP10-8 KRTAP12-2 KRTAP19-1 KRTAP6-2 LHX4 LIMS1 LZTS2 MID2 MKRN3 MORN3 MTUS2 MYLIP NBPF19 NOTCH2NLA PICK1 PIP4K2B PLAGL2 PNMA1 PNMA2 RBM39 RIMBP3C SOX13 SSX2IP STAC3 THAP1 TLE5 TNS2 TRAF2 TRIB3 TRIM27 TSPYL2 U2AF2 UIMC1 USH1G YAF2 ZNF526 ZNF552 ZRANB1
Entrez ID		55211	83444
HPRD ID		16836	17110
Ensembl ID		ENSG00000121570	ENSG00000115274
Uniprot IDs		Q7L190	Q9C086
PDB IDs			6HTS
Enriched GO Terms of Interacting Partners?
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