DPPA4 and SNX18

Data Source:
BioGRID (two hybrid)

		DPPA4	SNX18
Description		developmental pluripotency associated 4	sorting nexin 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Endosome Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Multicellular Organism Development Somatic Stem Cell Population Maintenance System Development	Mitotic Cytokinesis Endocytosis Protein Transport Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)	Immune response to smallpox vaccine (IL-6) ( 22542470)
Interacting Genes		35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM	19 interacting genes: ABI2 CPSF7 CYSRT1 DPPA4 GABARAP GOLGA2 HSF2BP HSPB2 HSPB2-C11orf52 KHDRBS3 KRTAP1-1 KRTAP6-3 MAP1LC3B MDFI MSS51 PTPN21 SOS1 SOS2 ZBTB42
Entrez ID		55211	112574
HPRD ID		16836	15407
Ensembl ID		ENSG00000121570	ENSG00000178996
Uniprot IDs		Q7L190	Q96RF0
PDB IDs
Enriched GO Terms of Interacting Partners?
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