UACA and MED14

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UACA	MED14
Description		uveal autoantigen with coiled-coil domains and ankyrin repeats	mediator complex subunit 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytosol Cytoskeleton Extracellular Exosome	Nucleus Nucleoplasm Membrane Mediator Complex Core Mediator Complex
	Molecular Function	Molecular_function Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding
	Biological Process	Biological_process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Apoptotic Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways		Regulation of the apoptosome activity	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Pulmonary function ( 23932459)	Migraine ( 27322543)
Interacting Genes		13 interacting genes: AHCYL1 ANKRD28 CCDC125 CELSR3 HIF1AN JPH1 KRT31 KRT40 MED14 PRKAR1B RTP2 STAMBP UBQLN2	20 interacting genes: ACTN1 ACTN2 AR CTDP1 DCTN1 ESR1 ESR2 FBXL17 HNF4A MED1 MED29 MED9 NECAB2 NR3C1 PARP1 PPARGC1A SREBF1 STAT2 UACA VDR
Entrez ID		55075	9282
HPRD ID		11657	02172
Ensembl ID		ENSG00000137831	ENSG00000180182
Uniprot IDs		Q9BZF9	O60244
PDB IDs
Enriched GO Terms of Interacting Partners?
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