FBXL12 and GEMIN4

Data Source:
BioGRID (two hybrid)

		FBXL12	GEMIN4
Description		F-box and leucine rich repeat protein 12	gem nuclear organelle associated protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol SCF Ubiquitin Ligase Complex	Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Membrane Nuclear Body Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Exosome Gemini Of Coiled Bodies
	Molecular Function	Protein Binding	Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Entrainment Of Circadian Clock By Photoperiod Post-translational Protein Modification Regulation Of Cell Cycle	Spliceosomal SnRNP Assembly RRNA Processing Import Into Nucleus
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	snRNP Assembly
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472)	Prostate cancer ( 23535732)
Interacting Genes		19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3	55 interacting genes: AGO2 ALPP CALCOCO2 CCDC185 CCT3 CDC20B CERCAM CFP DDX20 DHX9 DMPK FBXL12 FLAD1 GEMIN5 GLYR1 HR KANK2 KARS1 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 LGALS1 LGALS3 LY86 MORC4 NPPB NUFIP1 PIAS3 PSMB1 PTCD1 PTEN RAD51D RN7SL1 RNU1-1 RNU2-1 S1PR4 SNRPB SNRPD1 SNRPD2 SPG21 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TAP1 TOP1 UFC1 USP15 USP2 ZNF326 ZNF35
Entrez ID		54850	50628
HPRD ID		12363	07370
Ensembl ID		ENSG00000127452	ENSG00000179409
Uniprot IDs		Q9NXK8	I3L2C7 P57678 Q8WUM5
PDB IDs
Enriched GO Terms of Interacting Partners?
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