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RNF111 and TRAF5
Data Source:
BioGRID
(two hybrid)
RNF111
TRAF5
Description
ring finger protein 111
TNF receptor associated factor 5
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
PML Body
Protein-containing Complex
Centrosome
Cytosol
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Plasma Membrane Signaling Receptor Complex
Molecular Function
Protein Binding
SUMO Polymer Binding
SMAD Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Identical Protein Binding
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Pattern Specification Process
Protein Ubiquitination
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Ubiquitin-dependent SMAD Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Global Genome Nucleotide-excision Repair
Apoptotic Process
Signal Transduction
Positive Regulation Of Cell Population Proliferation
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JNK Cascade
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein K63-linked Ubiquitination
Pathways
Downregulation of SMAD2/3:SMAD4 transcriptional activity
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Formation of Incision Complex in GG-NER
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Asperger disorder (
21182207
)
Atopic dermatitis (
25865352
)
Cerebrospinal fluid AB1-42 levels (
28247064
)
Metabolite levels (
22916037
)
Social communication problems (
24047820
)
Household income (MTAG) (
31844048
)
Interacting Genes
54 interacting genes:
ACTN3
ANAPC11
AP2M1
AXIN1
CREB1
CREBBP
CSNK2A1
CTBP1
DTX3L
EDARADD
KRTAP1-1
KRTAP5-9
LCE4A
LRSAM1
MARCHF7
MDFI
MVP
NBPF19
NOTCH2NLA
PAX6
PHF7
PML
PSME3
PTPN3
SDCBP2
SMAD3
SMAD6
SMAD7
SMURF2
SUMO1
SUMO2
SUMO3
TRAF5
TRIM21
TRIM8
TSG101
TSPYL1
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2G2
UBE2I
UBE2K
UBE2M
UBE2N
UBE2Q2
UBE2V1
UBE2W
VAPB
66 interacting genes:
BEX3
CAPNS1
CCDC184
CD27
CD40
CDC37
CIB3
COG7
COMMD3
DGKH
ENOX2
FAM9A
FBXO28
GAS8
GOLGA2
GORASP2
HOMER1
HSD17B10
HSF2BP
LMO4
LNX1
LTBR
MAP3K14
MAP3K5
MDM2
MEOX2
NMI
NTAQ1
NUMBL
ODF2
PIAS2
PIBF1
PICK1
PSMA1
RAD23A
RIPK1
RIPK2
RNF111
RNF4
SDCBP
SEC13
SERPINB9
SUMO1
TBK1
TDP2
THAP1
THAP7
TNFRSF11A
TNFRSF12A
TNFRSF13B
TNFRSF14
TNFRSF19
TNFRSF4
TNFRSF8
TRAF2
TRAF3
TRAF3IP2
TRAF6
TRIM27
TRIM37
TRIM8
UBC
USP7
YPEL5
ZFAND6
ZNF655
Entrez ID
54778
7188
HPRD ID
09318
03834
Ensembl ID
ENSG00000157450
ENSG00000082512
Uniprot IDs
A0A024R5T5
Q6ZNA4
O00463
PDB IDs
2KIZ
5LG0
5LG7
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Intersection)
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