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PITX1 and SIK1B
Data Source:
BioGRID
(two hybrid)
PITX1
SIK1B
Description
paired like homeodomain 1
salt inducible kinase 1B (putative)
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Transcription Regulator Complex
Cytoplasm
Nucleus
Cytoplasm
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Skeletal System Development
Regulation Of Transcription By RNA Polymerase II
Anatomical Structure Morphogenesis
Branchiomeric Skeletal Muscle Development
Pituitary Gland Development
Embryonic Hindlimb Morphogenesis
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Myoblast Fate Commitment
Cartilage Development
Protein Phosphorylation
Intracellular Signal Transduction
Cellular Response To Glucose Starvation
Pathways
Circadian Clock
Drugs
Dabrafenib
Fostamatinib
Diseases
Congenital clubfoot; Congenital talipes equinovarus
GWAS
Atrial fibrillation (
29237688
)
Bulimia nervosa (
23568457
)
Colorectal cancer (
30529582
24836286
23263487
)
Colorectal cancer or advanced adenoma (
30510241
)
Height (
20881960
25429064
23563607
31562340
18391951
)
Immune response to anthrax vaccine (
22658931
)
Testicular germ cell tumor (
28604732
23666240
)
Interacting Genes
98 interacting genes:
ABHD11
AKAP8L
ALG13
ANKRD10
ARID5A
ATN1
BPIFA1
C10orf55
C11orf1
C19orf54
C1orf94
C9orf57
CDX4
CEACAM6
CYSRT1
DCTN3
DVL3
DZIP3
EFEMP2
EGR1
FAM168A
FAM168B
FOXO1
GATA1
GOLGA2
HGS
HOXA1
HSF4
HYI
IGFL2
IPO13
KLHL26
KRT34
KRT83
KRTAP13-1
KRTAP13-2
KRTAP19-5
KRTAP19-7
KRTAP26-1
KRTAP3-3
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
LASP1
LZTS2
MAGED1
METTL27
MGAT5B
MSX2
MYH7B
MYOZ3
NEUROD1
NHLRC4
NID2
NR5A1
PFDN5
PLA2G10
PLEKHB2
PLSCR1
PLSCR3
POU1F1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMB11
PTK6
RBPMS
RFX6
RHOXF2
RNF31
ROR2
SERGEF
SERPINE1
SIK1B
SLC15A2
SMARCA2
SPAG8
STH
TBX19
TBX22
TEKT5
TFAP2D
TLE5
TP53BP1
TRAF1
TRAPPC2
TRIM23
TSC1
UFSP1
UPF2
VGLL3
YPEL3
ZBTB32
ZNF34
6 interacting genes:
GINS4
LHX8
MESD
PITX1
PRTFDC1
TIMM10
Entrez ID
5307
102724428
HPRD ID
03688
Ensembl ID
ENSG00000069011
ENSG00000275993
Uniprot IDs
P78337
X5D9A5
A0A0B4J2F2
P57059
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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