NSG2 and SUPT4H1

Data Source:
BioGRID (two hybrid)

		NSG2	SUPT4H1
Description		neuronal vesicle trafficking associated 2	SPT4 homolog, DSIF elongation factor subunit
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Golgi Apparatus Integral Component Of Membrane Dendrite Cytoplasmic Vesicle Membrane Early Endosome Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Lysosomal Lumen Golgi Cis Cisterna Membrane	Nucleoplasm DSIF Complex
	Molecular Function	Protein Binding Clathrin Light Chain Binding	RNA Polymerase II Complex Binding Protein Binding Zinc Ion Binding Protein Heterodimerization Activity
	Biological Process	Dopamine Receptor Signaling Pathway Endosomal Transport Clathrin Coat Assembly	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715)	Eosinophil percentage of white cells ( 32888494) Mental health study participation (completed survey) ( 31263887) Refractive error ( 32231278)
Interacting Genes		17 interacting genes: ANKRD46 APOC1 C3orf52 CLEC7A HCFC1R1 NDUFA2 RIF1 RPS27 RRH SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768	11 interacting genes: ANXA5 APP EWSR1 HTATSF1 LRIF1 LRRK2 MFHAS1 NSG2 PDLIM1 SUPT5H XRCC5
Entrez ID		51617	6827
HPRD ID		13664	16026
Ensembl ID		ENSG00000170091	ENSG00000213246
Uniprot IDs		Q9Y328	P63272
PDB IDs			3H7H 5OIK 6GMH 6GML 6TED
Enriched GO Terms of Interacting Partners?
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