CRLF3 and VPS25

Data Source:
BioGRID (two hybrid)

		CRLF3	VPS25
Description		cytokine receptor like factor 3	vacuolar protein sorting 25 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Cycle Arrest	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Endosomal Transport Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Pathways			Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS		Birth weight ( 27680694) Chronic obstructive pulmonary disease ( 30804561) Height ( 28552196 18391951) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 29403010) Platelet distribution width ( 32888494)
Interacting Genes		10 interacting genes: APPL2 DDIT4L KCTD21 KDM1A L3MBTL3 LGALS14 MYOZ3 RBM14 VPS25 ZFP1	21 interacting genes: APIP ASPG B9D2 BEND5 BPIFA1 CHMP6 CRLF3 GPR35 LTB4R2 PICK1 REL RHOXF2 SDCBP2 SEPTIN14 SNF8 SPG21 SPRY2 SYCE1 TADA2A TRIM27 VPS36
Entrez ID		51379	84313
HPRD ID		16757	14396
Ensembl ID		ENSG00000176390	ENSG00000131475
Uniprot IDs		Q8IUI8	A0A024R1X3 Q9BRG1
PDB IDs			2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?
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