Wiki-Pi
About
Search
Browse
People
Updates
Search
CDK18 and CCNK
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CDK18
CCNK
Description
cyclin dependent kinase 18
cyclin K
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Nucleus
Cytoplasm
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Nucleoplasm
Cyclin/CDK Positive Transcription Elongation Factor Complex
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
Biological Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Regulation Of Cell Cycle
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Cell Cycle
Positive Regulation Of DNA-templated Transcription, Elongation
SnRNA Transcription By RNA Polymerase II
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Positive Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Serine 2 Residues
Pathways
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Coronary artery disease in type 1 diabetes (
29695241
)
Scalp hair shape (
26926045
)
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Interacting Genes
56 interacting genes:
AK8
APP
BLZF1
CBY2
CCDC102B
CCDC125
CCDC85B
CCDC88B
CCND3
CCNDBP1
CCNK
CEP76
EYA2
FSD2
GOLGA2
GOLGA6L9
GORASP2
HAP1
HMBOX1
HOMER3
HOOK2
INCA1
KIFC3
KRT15
KRT16
KRT31
KRT34
KRT40
KRT75
KRT86
LZTS2
MAD1L1
MID2
MIPOL1
MTUS2
NUTM1
PIBF1
PNMA1
PPFIA1
RABEP1
REL
SEC23A
TRAF1
TRAF2
TRIM27
TRIM50
TRIM54
TSGA10
TTC23
VPS28
VPS52
YWHAQ
ZNF426
ZNF438
ZNF774
ZRANB1
52 interacting genes:
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
CYSRT1
DDIT4L
DVL3
EFEMP2
FAM168B
FKBP6
HIVEP1
HMG20A
HNRNPH1
HNRNPH2
HOMEZ
HOXA1
HSFY1
HSFY2
KCNRG
KRTAP13-2
KRTAP19-6
KRTAP19-7
KRTAP4-12
KRTAP6-2
KRTAP8-1
LZTS2
MYCL
NDC80
NECAB2
OXER1
PIN1
POLR1C
POLR2A
POU6F2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RBPMS
RFX6
RHOXF2
RUNX1
STX11
TLE5
TSC22D4
USHBP1
USP54
ZNF446
Entrez ID
5129
8812
HPRD ID
01354
10352
Ensembl ID
ENSG00000117266
ENSG00000090061
Uniprot IDs
A0A024R980
A0A024R996
Q07002
Q59G02
A0A024R6K1
O75909
PDB IDs
2I53
4CXA
4NST
4UN0
5ACB
5EFQ
6B3E
6CKX
6TD3
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?