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CCNK and RHOXF2
Data Source:
HPRD
(two hybrid)
CCNK
RHOXF2
Description
cyclin K
Rhox homeobox family member 2
Image
No pdb structure
GO Annotations
Cellular Component
Cyclin K-CDK12 Complex
Cyclin K-CDK13 Complex
Nucleus
Nucleoplasm
Cyclin/CDK Positive Transcription Elongation Factor Complex
Chromatin
Nucleus
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Kinase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Cell Cycle
Positive Regulation Of DNA-templated Transcription, Elongation
SnRNA Transcription By RNA Polymerase II
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Positive Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Serine 2 Residues
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Gene Expression
Pathways
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Scalp hair shape (
26926045
)
Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) (
29455858
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Interacting Genes
52 interacting genes:
ATXN1
BHLHE40
CCDC85B
CDK18
CDK2
CDK9
CEP76
CYSRT1
DDIT4L
DVL3
EFEMP2
FAM168B
FKBP6
HIVEP1
HMG20A
HNRNPH1
HNRNPH2
HOMEZ
HOXA1
HSFY1
HSFY2
KCNRG
KRTAP13-2
KRTAP19-6
KRTAP19-7
KRTAP4-12
KRTAP6-2
KRTAP8-1
LZTS2
MYCL
NDC80
NECAB2
OXER1
PIN1
POLR1C
POLR2A
POU6F2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RBPMS
RFX6
RHOXF2
RUNX1
STX11
TLE5
TSC22D4
USHBP1
USP54
ZNF446
101 interacting genes:
ARID5A
ARMCX2
ARSA
ATN1
ATXN1
BATF3
BOLL
C1orf94
CAMK2A
CCDC33
CCNK
CEACAM6
CERCAM
CHAC1
CLASRP
CLDN7
CREM
CRX
CRYBA1
DAB1
DAZAP2
DEDD2
DTX2
DVL2
EFEMP2
EWSR1
FAM166A
FAM168A
FAM168B
FBF1
HNRNPLL
HOXC13
HYPK
KHDC4
KLHDC7B
KRTAP12-2
KRTAP13-2
KRTAP13-4
KRTAP15-1
KRTAP19-5
KRTAP19-6
KRTAP19-7
KRTAP26-1
KRTAP6-1
KRTAP6-2
KRTAP7-1
LASP1
LENG8
LSM4
LZTS2
MAGED1
MDFI
MED7
MGAT5B
MSX2
MVP
NANOG
NEU4
NKX1-2
NKX3-1
PITX1
PLAC8
PLOD3
POLR3D
POU2AF1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR34
PSMF1
RADIL
RAMAC
RBFOX1
RBFOX2
RBM11
RBPMS
RBPMS2
RNF4
SERF2
SNAPC1
SUMO1
TENT5A
TENT5B
TENT5C
TENT5D
TEP1
TLE5
TMCC2
TOLLIP
TRIP13
UBAP2
UBE2I
UPF1
UTP6
VAC14
VENTX
VPS25
ZBTB32
ZNF683
Entrez ID
8812
84528
HPRD ID
10352
02345
Ensembl ID
ENSG00000090061
ENSG00000131721
Uniprot IDs
A0A024R6K1
O75909
Q9BQY4
PDB IDs
2I53
4CXA
4NST
4UN0
5ACB
5EFQ
6B3E
6CKX
6TD3
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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