GLRX5 and BOLA1

Data Source:
BioGRID (pull down)

		GLRX5	BOLA1
Description		glutaredoxin 5	bolA family member 1
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Mitochondrion
	Molecular Function	Protein Binding Protein Disulfide Oxidoreductase Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding
	Biological Process	Hemopoiesis Small Molecule Metabolic Process [2Fe-2S] Cluster Assembly Protein Maturation By [2Fe-2S] Cluster Transfer Protein Maturation By [4Fe-4S] Cluster Transfer
Pathways		Mitochondrial iron-sulfur cluster biogenesis
Drugs
Diseases		Erythropoietic porphyria (EP), including: Erythropoietic protoporphyria (EPP); Congenital erythropoietic porphyria (CEP); Gunther Disease; X-linked erythropoietic protoporphyria (XLEPP) Sideroblastic anemia, including: Pyridoxine-refractory autosomal recessive sideroblastic anemia (PRARSA); X-linked sideroblastic anemia (XLSA); X-linked sideroblastic anemia with ataxia (ASAT)
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Diisocyanate-induced asthma ( 25918132) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Obesity-related traits ( 23251661) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: APP BOLA1 BOLA3 KEAP1	10 interacting genes: APP BIRC2 BIRC7 C1orf94 GLRX3 GLRX5 HDX TXNRD3 XIAP ZNF572
Entrez ID		51218	51027
HPRD ID		12659	13036
Ensembl ID		ENSG00000182512	ENSG00000178096
Uniprot IDs		A0A384MDT9 Q86SX6	Q9Y3E2
PDB IDs		2MMZ 2WUL	5LCI
Enriched GO Terms of Interacting Partners?
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