MYL1 and ACTA2

Data Source:
HPRD (in vitro)

		MYL1	ACTA2
Description		myosin light chain 1	actin alpha 2, smooth muscle
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Muscle Myosin Complex Myofibril Sarcomere	Extracellular Space Cytoplasm Cytosol Dynactin Complex Lamellipodium Filopodium Smooth Muscle Contractile Fiber Protein-containing Complex Cell Body Extracellular Exosome
	Molecular Function	Calcium Ion Binding Structural Constituent Of Muscle	ATP Binding Protein Kinase Binding
	Biological Process	Muscle Contraction Muscle Filament Sliding Cardiac Muscle Contraction	Muscle Contraction Regulation Of Blood Pressure Response To Virus Positive Regulation Of Gene Expression Vascular Associated Smooth Muscle Contraction Positive Regulation Of Transcription, DNA-templated Glomerular Mesangial Cell Development Mesenchyme Migration
Pathways		Striated Muscle Contraction	Smooth Muscle Contraction NOTCH4 Intracellular Domain Regulates Transcription
Drugs			Phenethyl Isothiocyanate
Diseases			Familial thoracic aortic aneurysm and dissection (TAAD); Aortic aneurysm familial thoracic type (AAT)
GWAS		Serum metabolite levels ( 23093944)	Arthritis (juvenile idiopathic) ( 33106285) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic lymphocytic leukemia ( 26956414 23770605) Immunoglobulin A ( 20694011) Lymphocyte percentage of white cells ( 32888494) Pulse pressure ( 30578418) Selective IgA deficiency ( 27723758)
Interacting Genes		7 interacting genes: ACTA1 ACTA2 ANKRD1 APP EPB41 IQGAP1 UBC	18 interacting genes: CCT4 CCT5 CFL1 CREBBP DNASE1 EP300 GC MINK1 MYL1 MYOC PCYT1B PRKCD SELE SHBG SNTA1 TMSB4X UBE3A YBX1
Entrez ID		4632	59
HPRD ID		01180	00031
Ensembl ID		ENSG00000168530	ENSG00000107796
Uniprot IDs		P05976	D2JYH4 P62736
PDB IDs
Enriched GO Terms of Interacting Partners?
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