ACTA2 and PCYT1B

Data Source:
HPRD (in vitro)

		ACTA2	PCYT1B
Description		actin alpha 2, smooth muscle	phosphate cytidylyltransferase 1, choline, beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Dynactin Complex Lamellipodium Filopodium Smooth Muscle Contractile Fiber Protein-containing Complex Cell Body Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane
	Molecular Function	ATP Binding Protein Kinase Binding	Choline-phosphate Cytidylyltransferase Activity Phosphatidylcholine Binding
	Biological Process	Muscle Contraction Regulation Of Blood Pressure Response To Virus Positive Regulation Of Gene Expression Vascular Associated Smooth Muscle Contraction Positive Regulation Of Transcription, DNA-templated Glomerular Mesangial Cell Development Mesenchyme Migration	Ovarian Follicle Development Phosphatidylcholine Biosynthetic Process CDP-choline Pathway Spermatogenesis
Pathways		Smooth Muscle Contraction NOTCH4 Intracellular Domain Regulates Transcription	Synthesis of PC
Drugs		Phenethyl Isothiocyanate	Choline Choline salicylate
Diseases		Familial thoracic aortic aneurysm and dissection (TAAD); Aortic aneurysm familial thoracic type (AAT)
GWAS		Arthritis (juvenile idiopathic) ( 33106285) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic lymphocytic leukemia ( 26956414 23770605) Immunoglobulin A ( 20694011) Lymphocyte percentage of white cells ( 32888494) Pulse pressure ( 30578418) Selective IgA deficiency ( 27723758)
Interacting Genes		18 interacting genes: CCT4 CCT5 CFL1 CREBBP DNASE1 EP300 GC MINK1 MYL1 MYOC PCYT1B PRKCD SELE SHBG SNTA1 TMSB4X UBE3A YBX1	8 interacting genes: ACTA1 ACTA2 APP ECPAS PAXIP1 PCYT1A TMEM43 VKORC1L1
Entrez ID		59	9468
HPRD ID		00031	05376
Ensembl ID		ENSG00000107796	ENSG00000102230
Uniprot IDs		D2JYH4 P62736	Q9Y5K3
PDB IDs
Enriched GO Terms of Interacting Partners?
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