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MYBL1 and HIPK2
Data Source:
BioGRID
(pull down)
MYBL1
HIPK2
Description
MYB proto-oncogene like 1
homeodomain interacting protein kinase 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
PML Body
RNA Polymerase II Transcription Regulator Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
RNA Polymerase II Activating Transcription Factor Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
SMAD Binding
Virion Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Mitotic Cell Cycle
Regulation Of Transcription, DNA-templated
Male Meiosis I
Spermatogenesis
Negative Regulation Of Transposition
Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
PiRNA Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Eye Development
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Transforming Growth Factor Beta Receptor Signaling Pathway
Smoothened Signaling Pathway
Adult Walking Behavior
Positive Regulation Of Cell Population Proliferation
Anterior/posterior Pattern Specification
Retina Layer Formation
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Modulation By Virus Of Host Process
Neuron Differentiation
Erythrocyte Differentiation
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of BMP Signaling Pathway
PML Body Organization
Positive Regulation Of Protein Binding
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Positive Regulation Of DNA Binding
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of JNK Cascade
Embryonic Camera-type Eye Morphogenesis
Voluntary Musculoskeletal Movement
Positive Regulation Of DNA-binding Transcription Factor Activity
Regulation Of Cell Cycle
Embryonic Retina Morphogenesis In Camera-type Eye
Lens Induction In Camera-type Eye
SMAD Protein Signal Transduction
Iris Morphogenesis
Cellular Response To Hypoxia
Intrinsic Apoptotic Signaling Pathway
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways
PIWI-interacting RNA (piRNA) biogenesis
YAP1- and WWTR1 (TAZ)-stimulated gene expression
SUMOylation of transcription cofactors
Physiological factors
Regulation of TP53 Activity through Phosphorylation
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of MECP2 expression and activity
Drugs
Fostamatinib
Diseases
GWAS
Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis (
26980576
)
Systolic blood pressure (
28135244
)
Interacting Genes
4 interacting genes:
CREBBP
HIPK2
NCL
NLK
52 interacting genes:
AATF
ABL1
BTRC
CBX3
CHMP4B
CREBBP
CUL1
CXCL1
DAXX
DDX39A
DDX39B
FBXW7
H2BC21
HMGA1
KAT2B
MAP3K7
MBP
MDM2
MECP2
MKNK1
MYB
MYBL1
NKX2-1
NKX2-5
NKX3-1
NLK
PARP1
PAX6
PML
PTCH1
RANBP9
RUNX1
SENP1
SIAH1
SIAH2
SIRT1
SKI
SMAD1
SMAD2
SMAD3
SP100
SUMO1
SUMO2
SUMO3
TP53
TP53INP1
TP63
TP73
TRADD
UBE2I
WSB1
ZBTB4
Entrez ID
4603
28996
HPRD ID
08868
06039
Ensembl ID
ENSG00000185697
ENSG00000064393
Uniprot IDs
P10243
Q495G0
Q9H2X6
PDB IDs
6P5S
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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