MYBL1 and NLK

Data Source:
BioGRID (enzymatic study)

		MYBL1	NLK
Description		MYB proto-oncogene like 1	nemo like kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding SH2 Domain Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Male Meiosis I Spermatogenesis Negative Regulation Of Transposition Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II PiRNA Biosynthetic Process	MAPK Cascade Regulation Of Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Peptidyl-threonine Phosphorylation Negative Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Serine Phosphorylation Of STAT Protein Protein Autophosphorylation Protein Stabilization
Pathways		PIWI-interacting RNA (piRNA) biogenesis	Ca2+ pathway
Drugs
Diseases
GWAS			Non-response to bupropion and depression ( 27622933)
Interacting Genes		4 interacting genes: CREBBP HIPK2 NCL NLK	25 interacting genes: ASGR1 ATXN1 CREBBP CUL1 FBXW5 FOXO4 FOXP3 GRN HIPK2 KRTAP10-1 KRTAP10-3 KRTAP4-2 KRTAP5-6 KRTAP5-9 LEF1 MYB MYBL1 NDOR1 QRICH1 RCHY1 SDR16C5 SKP2 STAT3 USP4 ZHX3
Entrez ID		4603	51701
HPRD ID		08868	17637
Ensembl ID		ENSG00000185697	ENSG00000087095
Uniprot IDs		P10243 Q495G0	A0A024QZ12 Q9UBE8
PDB IDs
Enriched GO Terms of Interacting Partners?
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