MX1 and LRRC4B

Data Source:
BioGRID (two hybrid)

		MX1	LRRC4B
Description		MX dynamin like GTPase 1	leucine rich repeat containing 4B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Nuclear Membrane Mitochondrial Membrane Dendritic Spine Head Perinuclear Region Of Cytoplasm Presynapse Postsynaptic Endocytic Zone Membrane	Plasma Membrane Presynaptic Membrane Cerebellar Mossy Fiber Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	Signaling Receptor Binding
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of Synapse Structure Or Activity Defense Response To Virus Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization	Positive Regulation Of Synapse Assembly Regulation Of Postsynaptic Density Assembly Synaptic Membrane Adhesion Regulation Of Presynapse Assembly
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		41 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623	1 interacting genes: MX1
Entrez ID		4599	94030
HPRD ID		00919	18985
Ensembl ID		ENSG00000157601	ENSG00000131409
Uniprot IDs		P20591	A0A024R4I8 Q9NT99
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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