MX1 and GMEB1

Data Source:
BioGRID (two hybrid)

		MX1	GMEB1
Description		MX dynamin like GTPase 1	glucocorticoid modulatory element binding protein 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Nuclear Membrane Mitochondrial Membrane Dendritic Spine Head Perinuclear Region Of Cytoplasm Presynapse Postsynaptic Endocytic Zone Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding Hsp27 Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of Synapse Structure Or Activity Defense Response To Virus Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Basophil count ( 32888494)
Interacting Genes		41 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623	15 interacting genes: ATF7IP CASP8 CASP9 CREBBP DNMT3L GMEB2 MX1 NCOA2 SMAD1 SMAD3 SNIP1 SPOP TRIM55 TRIM63 UBE2I
Entrez ID		4599	10691
HPRD ID		00919	16059
Ensembl ID		ENSG00000157601	ENSG00000162419
Uniprot IDs		P20591	B1AT47 B2RCN8 Q9Y692
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM	1OQJ
Enriched GO Terms of Interacting Partners?
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