MX1 and NDUFV3

Data Source:
BioGRID (proximity labelling technology)

		MX1	NDUFV3
Description		MX dynamin like GTPase 1	NADH:ubiquinone oxidoreductase subunit V3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Nuclear Membrane Mitochondrial Membrane Dendritic Spine Head Perinuclear Region Of Cytoplasm Presynapse Postsynaptic Endocytic Zone Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	RNA Binding Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of Synapse Structure Or Activity Defense Response To Virus Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial ATP Synthesis Coupled Electron Transport
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Respiratory electron transport Complex I biogenesis
Drugs			NADH Ubidecarenone
Diseases
GWAS
Interacting Genes		41 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623	1 interacting genes: PHYHIP
Entrez ID		4599	4731
HPRD ID		00919	03716
Ensembl ID		ENSG00000157601	ENSG00000160194
Uniprot IDs		P20591	P56181
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM	5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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