MT-ND1 and DHDDS

Data Source:
HPRD (two hybrid)

		MT-ND1	DHDDS
Description		NADH dehydrogenase subunit 1	dehydrodolichyl diphosphate synthase subunit
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Integral Component Of Membrane Dendrite Mitochondrial Membrane Neuronal Cell Body	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Dehydrodolichyl Diphosphate Synthase Complex
	Molecular Function	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Polyprenyltransferase Activity Protein Binding Dehydrodolichyl Diphosphate Synthase Activity Metal Ion Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Response To Organic Cyclic Compound Mitochondrial Respiratory Chain Complex I Assembly Response To Hydroperoxide Response To Drug	Dolichyl Diphosphate Biosynthetic Process Polyprenol Biosynthetic Process
Pathways		Respiratory electron transport Complex I biogenesis	Synthesis of Dolichyl-phosphate Defective DHDDS causes retinitis pigmentosa 59
Drugs		NADH Methoxyflurane Halothane Desflurane Sevoflurane N-Formylmethionine Phenethyl Isothiocyanate
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS			FEV1 ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		12 interacting genes: BARD1 BRCA1 DHDDS FAT1 LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 SIRPA TST	3 interacting genes: LOX MT-ND1 NPC2
Entrez ID		4535	79947
HPRD ID		08365	12183
Ensembl ID		ENSG00000198888	ENSG00000117682
Uniprot IDs		P03886 U5Z754	Q86SQ9
PDB IDs		5XTC 5XTD	6W2L 6Z1N
Enriched GO Terms of Interacting Partners?
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