MT-ND1 and NDUFS7

Data Source:
HPRD (in vitro)

		MT-ND1	NDUFS7
Description		NADH dehydrogenase subunit 1	NADH:ubiquinone oxidoreductase core subunit S7
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Integral Component Of Membrane Dendrite Mitochondrial Membrane Neuronal Cell Body	Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix
	Molecular Function	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Response To Organic Cyclic Compound Mitochondrial Respiratory Chain Complex I Assembly Response To Hydroperoxide Response To Drug	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Respiratory electron transport Complex I biogenesis	Respiratory electron transport Complex I biogenesis
Drugs		NADH Methoxyflurane Halothane Desflurane Sevoflurane N-Formylmethionine Phenethyl Isothiocyanate	NADH
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)	Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		12 interacting genes: BARD1 BRCA1 DHDDS FAT1 LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 SIRPA TST	3 interacting genes: ARRB2 ENO2 MT-ND1
Entrez ID		4535	374291
HPRD ID		08365	03491
Ensembl ID		ENSG00000198888	ENSG00000115286
Uniprot IDs		P03886 U5Z754	O75251 Q6ZS38 Q7LD69
PDB IDs		5XTC 5XTD	5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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