CCDC88C and TAZ

Data Source:
BioGRID (affinity chromatography technology)

		CCDC88C	TAZ
Description		coiled-coil domain containing 88C	tafazzin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cell Junction	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity Frizzled Binding Protein Binding Microtubule Binding PDZ Domain Binding Identical Protein Binding Protein Self-association Dynein Light Intermediate Chain Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity
	Biological Process	Regulation Of Protein Phosphorylation Apical Constriction Small GTPase Mediated Signal Transduction Cytoskeleton-dependent Intracellular Transport Stress-activated Protein Kinase Signaling Cascade Cytoplasmic Microtubule Organization Protein Destabilization Non-canonical Wnt Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Canonical Wnt Signaling Pathway	Muscle Contraction Inner Mitochondrial Membrane Organization Heart Development Skeletal Muscle Tissue Development Hemopoiesis Cardiolipin Biosynthetic Process Mitochondrial Respiratory Chain Complex I Assembly Cardiolipin Acyl-chain Remodeling Cristae Formation Mitochondrial ATP Synthesis Coupled Electron Transport Cardiac Muscle Tissue Development Cardiac Muscle Contraction
Pathways		Negative regulation of TCF-dependent signaling by DVL-interacting proteins	Mitochondrial protein import Mitochondrial protein import Acyl chain remodeling of CL
Drugs
Diseases			3-Methylglutaconic aciduria (MGCA) Barth syndrome (BTHS) Dilated cardiomyopathy (DCM)
GWAS		Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683 23535729) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Daytime sleep phenotypes ( 27126917) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: APP DVL1 FBXO7 GNAI3 ITSN2 MAPK8	9 interacting genes: BTRC CHGB CSNK1E GSK3B LATS1 LATS2 RUNX1 SLC9A3R2 YWHAE
Entrez ID		440193	6901
HPRD ID		19136	02316
Ensembl ID		ENSG00000015133	ENSG00000102125
Uniprot IDs		B4DZB8 Q9P219	A0A0S2Z4E6 A0A0S2Z4F4 A0A0S2Z4K0 A0A0S2Z4K9 A0A494C0C5 A0A499FJ53 A6XNE1 Q16635
PDB IDs
Enriched GO Terms of Interacting Partners?
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