MPP1 and MAP3K20

Data Source:
BioGRID (two hybrid)

		MPP1	MAP3K20
Description		membrane palmitoylated protein 1	mitogen-activated protein kinase kinase kinase 20
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite	Nucleus Cytoplasm Cytosol
	Molecular Function	Guanylate Kinase Activity Protein Binding	Magnesium Ion Binding RNA Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding
	Biological Process	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis	DNA Damage Checkpoint Activation Of MAPKK Activity Protein Phosphorylation Cytoskeleton Organization Cell Cycle Arrest Activation Of JUN Kinase Activity Cell Death Cell Differentiation Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Limb Development Cellular Response To Gamma Radiation Positive Regulation Of Mitotic DNA Damage Checkpoint
Pathways
Drugs			Dasatinib Fostamatinib
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Interacting Genes		43 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID BHLHB9 DERL2 DGAT2L6 DNPEP ERBIN GADD45A GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639	32 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP1 ZFP2 ZNF33A ZNF35 ZNF567 ZNF593 ZNF660 ZNF71 ZNF746 ZNF775
Entrez ID		4354	51776
HPRD ID		02370	11791
Ensembl ID		ENSG00000130830	ENSG00000091436
Uniprot IDs		B4E325 Q00013	D4Q8H0 Q9NYL2
PDB IDs		2EJY 2EV8 3NEY	5HES 5X5O 6JUT 6JUU
Enriched GO Terms of Interacting Partners?
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