MPP1 and ABCC4

Data Source:
BioGRID (fluorescent resonance energy transfer)

		MPP1	ABCC4
Description		membrane palmitoylated protein 1	ATP binding cassette subfamily C member 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite	Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Platelet Dense Granule Membrane External Side Of Apical Plasma Membrane
	Molecular Function	Guanylate Kinase Activity Protein Binding	Protein Binding ATP Binding Purine Nucleotide Transmembrane Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Efflux Transmembrane Transporter Activity Ion Transmembrane Transporter Activity, Phosphorylative Mechanism 15-hydroxyprostaglandin Dehydrogenase (NAD+) Activity ATPase Activity ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis	Platelet Degranulation Response To Organonitrogen Compound Response To Organic Cyclic Compound Prostaglandin Secretion Bile Acid Signaling Pathway Response To Drug Xenobiotic Transport Positive Regulation Of Smooth Muscle Cell Proliferation Transmembrane Transport Cilium Assembly CAMP Transport Leukotriene Transport Anion Transmembrane Transport Export Across Plasma Membrane Transport Across Blood-brain Barrier
Pathways			Platelet degranulation ABC-family proteins mediated transport
Drugs			ATP
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)	Acute post-radiotherapy pain in breast cancer ( 31196165) Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Blood metabolite levels ( 24816252) Breast cancer ( 17903305) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Longevity ( 20834067) Parent of origin effect on language impairment (paternal) ( 24571439) Platelet count ( 22139419 29403010 32888494 27863252) Plateletcrit ( 32888494 27863252) Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer ( 23478653)
Interacting Genes		43 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID BHLHB9 DERL2 DGAT2L6 DNPEP ERBIN GADD45A GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639	6 interacting genes: ERBIN MPP1 PDZK1 SLC9A3R1 SLC9A3R2 SNTA1
Entrez ID		4354	10257
HPRD ID		02370	05583
Ensembl ID		ENSG00000130830	ENSG00000125257
Uniprot IDs		B4E325 Q00013	A8K2Q2 O15439
PDB IDs		2EJY 2EV8 3NEY
Enriched GO Terms of Interacting Partners?
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