Wiki-Pi
About
Search
Browse
People
Updates
Search
AFDN and NECTIN4
Data Source:
HPRD
(in vitro)
AFDN
NECTIN4
Description
afadin, adherens junction formation factor
nectin cell adhesion molecule 4
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytosol
Plasma Membrane
Cell-cell Junction
Adherens Junction
Nuclear Speck
Cell Junction
Cell-cell Contact Zone
Pore Complex
Tight Junction
Plasma Membrane
Adherens Junction
Integral Component Of Membrane
Extracellular Exosome
Molecular Function
Protein Binding
Protein C-terminus Binding
Small GTPase Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Actin Filament Binding
Virus Receptor Activity
Protein Binding
Identical Protein Binding
Biological Process
Cell Adhesion
Signal Transduction
Cell-cell Signaling
Positive Regulation Of Gene Expression
Positive Regulation Of Cell-cell Adhesion
Negative Regulation Of Cell Migration
Regulation Of Protein Localization
Adherens Junction Organization
Positive Regulation Of GTPase Activity
Cell-cell Adhesion Mediated By Cadherin
Pore Complex Assembly
Establishment Of Protein Localization To Plasma Membrane
Bicellular Tight Junction Assembly
Establishment Of Endothelial Intestinal Barrier
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Adherens Junction Organization
Viral Entry Into Host Cell
Pathways
Adherens junctions interactions
Nectin/Necl trans heterodimerization
Drugs
(5R)-2-sulfanyl-5-[4-(trifluoromethyl)benzyl]-1,3-thiazol-4(5H)-one
Enfortumab vedotin
Diseases
Ectodermal dysplasia-syndactyly syndrome (EDSS)
GWAS
Number of alcoholic drinks required to feel an effect (long-term average) (
31270906
)
Interacting Genes
37 interacting genes:
BCR
CTNNA1
EPHA7
EPHB2
EPHB3
EPHB6
F11R
HRAS
JAG1
LMO2
MRAS
NECTIN1
NECTIN2
NECTIN3
NECTIN4
NRXN1
NRXN2
NRXN3
PFN1
PICK1
RALGDS
RAP1A
RAP1GAP
RAP2A
RIN1
RIT1
RIT2
RRAS
RRAS2
SMAD2
SORBS1
SORBS2
SSX2IP
TJP1
USP9X
YWHAB
YWHAG
6 interacting genes:
AFDN
DEFB121
NECTIN1
NECTIN2
PICK1
TIGIT
Entrez ID
4301
81607
HPRD ID
01164
17934
Ensembl ID
ENSG00000130396
ENSG00000143217
Uniprot IDs
A8MQ02
G1UI22
J3KN01
P55196
K4PZ75
Q96NY8
PDB IDs
1T2M
1XZ9
2AIN
2EXG
5A6C
4FRW
4GJT
4JJH
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?