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MAOB and NFYB
Data Source:
BioGRID
(two hybrid)
MAOB
NFYB
Description
monoamine oxidase B
nuclear transcription factor Y subunit beta
Image
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Envelope
Mitochondrial Outer Membrane
Integral Component Of Membrane
Chromatin
Nucleus
Nucleoplasm
CCAAT-binding Factor Complex
Protein-DNA Complex
RNA Polymerase II Transcription Regulator Complex
Molecular Function
Protein Binding
Primary Amine Oxidase Activity
Electron Transfer Activity
Identical Protein Binding
Flavin Adenine Dinucleotide Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Heterodimerization Activity
Repressing Transcription Factor Binding
Biological Process
Response To Toxic Substance
Response To Aluminum Ion
Response To Selenium Ion
Negative Regulation Of Serotonin Secretion
Substantia Nigra Development
Electron Transport Chain
Response To Lipopolysaccharide
Neurotransmitter Catabolic Process
Dopamine Catabolic Process
Response To Drug
Response To Ethanol
Positive Regulation Of Dopamine Metabolic Process
Hydrogen Peroxide Biosynthetic Process
Response To Corticosterone
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Regulation Of Cholesterol Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
PPARA activates gene expression
Activation of gene expression by SREBF (SREBP)
Activation of gene expression by SREBF (SREBP)
ATF4 activates genes in response to endoplasmic reticulum stress
ATF6 (ATF6-alpha) activates chaperone genes
ATF6 (ATF6-alpha) activates chaperone genes
FOXO-mediated transcription of cell death genes
Drugs
Amphetamine
Amphetamine
Phentermine
Procaine
Tranylcypromine
Phenelzine
Zonisamide
Selegiline
Pioglitazone
Procarbazine
Moclobemide
Moclobemide
Isocarboxazid
Ephedra sinica root
Rasagiline
MMDA
4-Methoxyamphetamine
Metamfetamine
Pargyline
Isatin
(R)-N-methyl-N-2-propynyl-1-indanamine
Farnesol
N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate
Flavin adenine dinucleotide
N-Propargyl-1(S)-Aminoindan
Dodecyldimethylamine N-oxide
5-Hydroxy-N-Propargyl-1(R)-Aminoindan
N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE
Nialamide
Nomifensine
Zimelidine
Safinamide
7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE
7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE
N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE
(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE
4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN
(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE]
Flortaucipir F-18
Diseases
GWAS
Toenail selenium levels (
25343990
)
Interacting Genes
6 interacting genes:
COX20
FGF14
NFYB
RHBDD2
SRPK1
TRIM54
26 interacting genes:
AGTRAP
C1QBP
CEBPZ
CIITA
CNTN2
DRAP1
ELF1
EP300
GRB2
MAOB
MEOX2
MYC
NFYA
NFYC
POLE4
POU3F2
SMYD3
SP1
TAF11
TAF12
TAF6
TBP
TP53
TP73
YBX1
YBX3
Entrez ID
4129
4801
HPRD ID
02401
01794
Ensembl ID
ENSG00000069535
ENSG00000120837
Uniprot IDs
B7Z242
P27338
A0A024RBG7
F8VSL3
P25208
PDB IDs
1GOS
1H8R
1OJ9
1OJA
1OJC
1OJD
1S2Q
1S2Y
1S3B
1S3E
2BK3
2BK4
2BK5
2BYB
2C64
2C65
2C66
2C67
2C70
2C72
2C73
2C75
2C76
2V5Z
2V60
2V61
2VRL
2VRM
2VZ2
2XCG
2XFN
2XFO
2XFP
2XFQ
2XFU
3PO7
3ZYX
4A79
4A7A
4CRT
5MRL
6FVZ
6FW0
6FWC
6RKB
6RKP
6RLE
6YT2
1N1J
4AWL
4CSR
6QMP
6QMQ
6QMS
Enriched GO Terms of Interacting Partners
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