NFYB and TAF12

Data Source:
BioGRID (pull down)

		NFYB	TAF12
Description		nuclear transcription factor Y subunit beta	TATA-box binding protein associated factor 12
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity Repressing Transcription Factor Binding	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator
Pathways		PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Toenail selenium levels ( 25343990)	Type 2 diabetes ( 31049640)
Interacting Genes		26 interacting genes: AGTRAP C1QBP CEBPZ CIITA CNTN2 DRAP1 ELF1 EP300 GRB2 MAOB MEOX2 MYC NFYA NFYC POLE4 POU3F2 SMYD3 SP1 TAF11 TAF12 TAF6 TBP TP53 TP73 YBX1 YBX3	23 interacting genes: ATF7 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		4801	6883
HPRD ID		01794	15981
Ensembl ID		ENSG00000120837	ENSG00000120656
Uniprot IDs		A0A024RBG7 F8VSL3 P25208	Q16514
PDB IDs		1N1J 4AWL 4CSR 6QMP 6QMQ 6QMS	1H3O 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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