MAGEA2 and TNIP3

Data Source:
BioGRID (two hybrid)

		MAGEA2	TNIP3
Description		MAGE family member A2	TNFAIP3 interacting protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body	Cytosol
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Repressing Transcription Factor Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Sumoylation Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation	MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Protein Deubiquitination Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide
Pathways			Ovarian tumor domain proteases
Drugs
Diseases
GWAS			Breast cancer ( 23468962) Multiple sclerosis ( 31604244)
Interacting Genes		21 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 COQ4 COX7C DYNLRB1 MBD3 MDM2 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TP53 TRIM28	27 interacting genes: CCN3 CYSRT1 DAZAP2 FAM161A KPNA3 KRT40 KRTAP10-3 KRTAP10-8 LITAF LZTS2 MAGEA2 MAGEA2B MTUS2 NBPF19 NOTCH2NLA NTAQ1 PIBF1 PLSCR3 TAX1BP1 TCEANC TNFAIP3 TNIP1 TRIM55 TRIM63 TRIM8 UBC ZBTB8A
Entrez ID		4101	79931
HPRD ID		02165	16268
Ensembl ID		ENSG00000268606	ENSG00000050730
Uniprot IDs		A0A024RC17 P43356 Q6P448	Q96KP6
PDB IDs
Enriched GO Terms of Interacting Partners?
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