MAGEA2 and PHKG2

Data Source:
BioGRID (two hybrid)

		MAGEA2	PHKG2
Description		MAGE family member A2	phosphorylase kinase catalytic subunit gamma 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus PML Body	Cytosol Phosphorylase Kinase Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Repressing Transcription Factor Binding	Protein Serine/threonine Kinase Activity Phosphorylase Kinase Activity Protein Binding Calmodulin Binding ATP Binding Tau-protein Kinase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Protein Sumoylation Cellular Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Signal Transduction By P53 Class Mediator Cellular Senescence Negative Regulation Of Protein Acetylation	Glycogen Metabolic Process Glycogen Biosynthetic Process Glycogen Catabolic Process Generation Of Precursor Metabolites And Energy Protein Phosphorylation Positive Regulation Of Glycogen Catabolic Process
Pathways			Glycogen breakdown (glycogenolysis)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS
Interacting Genes		21 interacting genes: ACSM1 ANKRD45 BEX1 BEX2 CCDC185 CEP57 COQ4 COX7C DYNLRB1 MBD3 MDM2 NTAQ1 P4HA3 PHKG2 POLL PSMC1 SEPTIN5 SMARCD1 TNIP3 TP53 TRIM28	5 interacting genes: DAPK1 MAGEA2 MAGEA2B PHKA2 PHKG1
Entrez ID		4101	5261
HPRD ID		02165	01405
Ensembl ID		ENSG00000268606	ENSG00000156873
Uniprot IDs		A0A024RC17 P43356 Q6P448	P15735
PDB IDs			2Y7J
Enriched GO Terms of Interacting Partners?
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