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MIRLET7B and IARS1
Data Source:
BioGRID
(unspecified method)
MIRLET7B
IARS1
Description
microRNA let-7b
isoleucyl-tRNA synthetase 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
Extracellular Exosome
Molecular Function
MRNA Binding Involved In Posttranscriptional Gene Silencing
TRNA Binding
Aminoacyl-tRNA Editing Activity
Isoleucine-tRNA Ligase Activity
Protein Binding
ATP Binding
GTPase Binding
Biological Process
Negative Regulation Of Autophagy
Cellular Response To Reactive Oxygen Species
Gene Silencing By MiRNA
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Osteoblast Differentiation
TRNA Aminoacylation For Protein Translation
Isoleucyl-tRNA Aminoacylation
Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Drugs
Isoleucine
Diseases
GWAS
Interacting Genes
99 interacting genes:
ADARB1
AGO2
AIMP1
AIMP2
APOBEC3B
ATXN2L
C1QBP
CELF1
CPSF1
CPSF6
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX23
DDX3X
DDX3Y
DHX36
DHX37
EIF2AK2
ELAVL1
EPRS1
ERAL1
ESRP1
FAM98A
FIP1L1
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
P3H1
PDCD11
PGAM5
PLOD1
PTBP1
PUF60
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RBM4B
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
SYMPK
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
TUT7
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
76 interacting genes:
APP
AR
CDC42
DUX4
EPRS1
ERBB2
GARS1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
SUMO2
Entrez ID
406884
3376
HPRD ID
02832
Ensembl ID
ENSG00000284520
ENSG00000196305
Uniprot IDs
P41252
Q6P0M4
Q7L4K8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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