MIRLET7B and PUM2

Data Source:
BioGRID (unspecified method)

		MIRLET7B	PUM2
Description		microRNA let-7b	pumilio RNA binding family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome Extracellular Vesicle	Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding MiRNA Binding
	Biological Process	Negative Regulation Of Autophagy Cellular Response To Reactive Oxygen Species Gene Silencing By MiRNA Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Angiogenesis Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis	Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Stress Granule Assembly Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of MRNA Stability Regulation Of Chromosome Segregation Regulation Of Gene Silencing By MiRNA Positive Regulation Of RIG-I Signaling Pathway Positive Regulation Of Gene Silencing By MiRNA
Pathways			Neddylation
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Body mass index ( 28892062) Low density lipoprotein cholesterol levels ( 32154731)
Interacting Genes		99 interacting genes: ADARB1 AGO2 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CELF1 CPSF1 CPSF6 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAVL1 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PLOD1 PTBP1 PUF60 PUM2 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RBM4B RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	24 interacting genes: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 MIR128-2 MIR17 MIR199A1 MIR199A2 MIR214 MIR221 MIR7-1 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G NANOS1
Entrez ID		406884	23369
HPRD ID			09527
Ensembl ID		ENSG00000284520	ENSG00000055917
Uniprot IDs			A0A0A0MR59 B7ZL34 Q8TB72
PDB IDs			3Q0Q 3Q0R 3Q0S
Enriched GO Terms of Interacting Partners?
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