SOHLH1 and SUOX

Data Source:
BioGRID (two hybrid)

		SOHLH1	SUOX
Description		spermatogenesis and oogenesis specific basic helix-loop-helix 1	sulfite oxidase
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Protein Binding Sulfite Oxidase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Oocyte Differentiation Cell Differentiation	Sulfur Compound Metabolic Process Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase
Pathways			Sulfide oxidation to sulfate
Drugs			{[2-Amino-4-oxo-6,7-di(sulfanyl-ÎºS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 32296059 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 18198356 31152121) Vitiligo ( 22951725)
Interacting Genes		26 interacting genes: ACTN3 ARID5A C10orf55 CASP3 CERCAM CTAG1A CTAG1B DTX2 FAM222B HEMK1 IL16 KRTAP19-5 NUP54 OIP5 PEF1 PFDN5 PRKAA2 PSMB4 RUSC1 STH SUOX TENT5B TLE5 TRAF1 USHBP1 ZMYND12	77 interacting genes: ACOT11 BAG4 C1D C5orf51 CAMK2A CCDC103 CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RINT1 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC
Entrez ID		402381	6821
HPRD ID		16678	06055
Ensembl ID		ENSG00000165643	ENSG00000139531
Uniprot IDs		Q5JUK2	A0A024RB79 P51687
PDB IDs			1MJ4
Enriched GO Terms of Interacting Partners?
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