SOHLH1 and FAM222B

Data Source:
BioGRID (two hybrid)

		SOHLH1	FAM222B
Description		spermatogenesis and oogenesis specific basic helix-loop-helix 1	family with sequence similarity 222 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Oocyte Differentiation Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Estimated glomerular filtration rate reduction (30%) ( 30955190) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Red blood cell count ( 32888494) Red cell distribution width ( 27863252)
Interacting Genes		26 interacting genes: ACTN3 ARID5A C10orf55 CASP3 CERCAM CTAG1A CTAG1B DTX2 FAM222B HEMK1 IL16 KRTAP19-5 NUP54 OIP5 PEF1 PFDN5 PRKAA2 PSMB4 RUSC1 STH SUOX TENT5B TLE5 TRAF1 USHBP1 ZMYND12	35 interacting genes: ANKRD10 BAG4 BANP BPIFA1 C10orf55 C19orf54 CDCA4 CNFN FAM168B FHL3 FOSB HYI INTS11 KRTAP11-1 KRTAP26-1 KRTAP3-1 LRRC61 OIP5 PDLIM4 PFDN5 PLA2G10 PRR20A PRR20B PRR20C PRR20D PRR20E RUNX1 SOHLH1 TRIP6 TSC1 TTLL12 UBQLN2 UFSP1 WWOX ZMYND12
Entrez ID		402381	55731
HPRD ID		16678	07693
Ensembl ID		ENSG00000165643	ENSG00000173065
Uniprot IDs		Q5JUK2	A0A024QZ60 B3KQ88 B3KTH5 B4DRX9 Q8WU58
PDB IDs
Enriched GO Terms of Interacting Partners?
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