LIPE and PLIN1

Data Source:
BioGRID (fluorescent resonance energy transfer, protein complementation assay, fluorescent resonance energy transfer, affinity chromatography technology)

		LIPE	PLIN1
Description		lipase E, hormone sensitive type	perilipin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lipid Droplet Cytosol Caveola Membrane	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Sterol Esterase Activity Triglyceride Lipase Activity Protein Binding Hormone-sensitive Lipase Activity Acylglycerol Lipase Activity Retinyl-palmitate Esterase Activity 1,3-diacylglycerol Acylhydrolase Activity 1,2-diacylglycerol Acylhydrolase Activity	Lipid Binding
	Biological Process	Protein Phosphorylation Cholesterol Metabolic Process Lipid Catabolic Process Triglyceride Catabolic Process Retinol Metabolic Process Diacylglycerol Catabolic Process Ether Lipid Metabolic Process	Lipid Metabolic Process Lipid Catabolic Process
Pathways		Triglyceride catabolism	Triglyceride catabolism Transcriptional regulation of white adipocyte differentiation NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose
Drugs
Diseases
GWAS			HDL cholesterol ( 30275531)
Interacting Genes		11 interacting genes: FABP4 KATNA1 MAPK1 MAPK3 MTNR1A NSFL1C PLIN1 PLIN5 PRKACA STAR TSGA10IP	4 interacting genes: ABHD5 BSCL2 LIPE PRKACA
Entrez ID		3991	5346
HPRD ID		01062	01364
Ensembl ID		ENSG00000079435	ENSG00000166819
Uniprot IDs		A8K8W7 Q05469	O60240
PDB IDs
Enriched GO Terms of Interacting Partners?
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