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LIPE and FABP4
Data Source:
BioGRID
(fluorescent resonance energy transfer)
HPRD
(two hybrid, in vitro, in vivo)
LIPE
FABP4
Description
lipase E, hormone sensitive type
fatty acid binding protein 4
Image
No pdb structure
GO Annotations
Cellular Component
Lipid Droplet
Cytosol
Caveola
Membrane
Nucleus
Cytoplasm
Lipid Droplet
Cytosol
Extracellular Exosome
Molecular Function
Sterol Esterase Activity
Triglyceride Lipase Activity
Protein Binding
Hormone-sensitive Lipase Activity
Acylglycerol Lipase Activity
Retinyl-palmitate Esterase Activity
1,3-diacylglycerol Acylhydrolase Activity
1,2-diacylglycerol Acylhydrolase Activity
Long-chain Fatty Acid Transporter Activity
Fatty Acid Binding
Long-chain Fatty Acid Binding
Hormone Receptor Binding
Biological Process
Protein Phosphorylation
Cholesterol Metabolic Process
Lipid Catabolic Process
Triglyceride Catabolic Process
Retinol Metabolic Process
Diacylglycerol Catabolic Process
Ether Lipid Metabolic Process
Negative Regulation Of Protein Kinase Activity
Response To Bacterium
Long-chain Fatty Acid Transport
Triglyceride Catabolic Process
Cholesterol Homeostasis
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Inflammatory Response
White Fat Cell Differentiation
Brown Fat Cell Differentiation
Cellular Response To Lithium Ion
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Cold-induced Thermogenesis
Pathways
Triglyceride catabolism
Triglyceride catabolism
Triglyceride catabolism
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Metabolite levels (
23823483
)
Ovarian cancer (
23535730
)
Visceral fat (
22589738
)
Interacting Genes
11 interacting genes:
FABP4
KATNA1
MAPK1
MAPK3
MTNR1A
NSFL1C
PLIN1
PLIN5
PRKACA
STAR
TSGA10IP
8 interacting genes:
ACP1
ACTB
CHD3
INSR
LIPE
PRKCI
VIM
ZBED1
Entrez ID
3991
2167
HPRD ID
01062
02698
Ensembl ID
ENSG00000079435
ENSG00000170323
Uniprot IDs
A8K8W7
Q05469
E7DVW4
P15090
PDB IDs
1TOU
1TOW
2HNX
2NNQ
3FR2
3FR4
3FR5
3P6C
3P6D
3P6E
3P6F
3P6G
3P6H
3Q6L
3RZY
4NNS
4NNT
5D45
5D47
5D48
5D4A
5EDB
5EDC
5HZ6
5HZ8
5Y0F
5Y0G
5Y0X
5Y12
5Y13
6AYL
6LJS
6LJT
6LJU
6LJV
6LJW
6LJX
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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