KRT3 and HYI

Data Source:
BioGRID (two hybrid)

		KRT3	HYI
Description		keratin 3	hydroxypyruvate isomerase (putative)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cellular_component
	Molecular Function	Protein Binding	Molecular_function Protein Binding Hydroxypyruvate Isomerase Activity
	Biological Process	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Cornification	Biological_process Glyoxylate Metabolic Process
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Meesmann corneal dystrophy
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		40 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT14 KRT16 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT75 KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426	14 interacting genes: CCDC24 FAM222B GPANK1 INCA1 KRT3 PATZ1 PITX1 POGZ SHBG SRSF11 TEX11 TLX3 USHBP1 VPS37C
Entrez ID		3850	81888
HPRD ID		01013	11039
Ensembl ID		ENSG00000186442	ENSG00000178922
Uniprot IDs		P12035	A0A0A0MTR5 F6UJY1 Q5T013
PDB IDs
Enriched GO Terms of Interacting Partners?
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