KRT3 and BPIFA1

Data Source:
BioGRID (two hybrid)

		KRT3	BPIFA1
Description		keratin 3	BPI fold containing family A member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding	Molecular_function Protein Binding Lipid Binding
	Biological Process	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Cornification	Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antimicrobial Humoral Response Antibacterial Humoral Response Innate Immune Response Regulation Of Liquid Surface Tension Multicellular Organismal Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport
Pathways		Keratinization Formation of the cornified envelope	Antimicrobial peptides
Drugs
Diseases		Meesmann corneal dystrophy
GWAS
Interacting Genes		40 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT14 KRT16 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT75 KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426	50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765
Entrez ID		3850	51297
HPRD ID		01013	07594
Ensembl ID		ENSG00000186442	ENSG00000198183
Uniprot IDs		P12035	Q9NP55
PDB IDs			4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L
Enriched GO Terms of Interacting Partners?
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