ACAT1 and PEX7

Data Source:
BioGRID (two hybrid)

		ACAT1	PEX7
Description		acetyl-CoA acetyltransferase 1	peroxisomal biogenesis factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Extracellular Exosome	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol
	Molecular Function	Acetyl-CoA C-acetyltransferase Activity C-acetyltransferase Activity Potassium Ion Binding	Peroxisome Matrix Targeting Signal-2 Binding Protein Binding Enzyme Binding Protein Homodimerization Activity
	Biological Process	Acetyl-CoA Biosynthetic Process Isoleucine Catabolic Process Fatty Acid Beta-oxidation Branched-chain Amino Acid Catabolic Process Coenzyme A Metabolic Process Coenzyme A Biosynthetic Process Cholesterol Esterification Acetyl-CoA Catabolic Process Ketone Body Biosynthetic Process Ketone Body Catabolic Process Ketone Body Metabolic Process Propionyl-CoA Biosynthetic Process	Neuron Migration Endochondral Ossification Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Peroxisome Organization Ether Lipid Biosynthetic Process Protein Import Into Peroxisome Matrix
Pathways		Branched-chain amino acid catabolism Utilization of Ketone Bodies Synthesis of Ketone Bodies	Peroxisomal protein import Peroxisomal protein import
Drugs		Sulfasalazine Cannabidiol Medical Cannabis Nabiximols
Diseases			Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3) Refsum disease; Heredopathia atactica polyneuritiformis
GWAS		Nonunion in individuals with fractures ( 30680360) Refractive error ( 32231278)	Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		4 interacting genes: AGXT PDP1 PEX7 PTPRF	8 interacting genes: ACAT1 KDM1A PEX13 PEX14 PEX5 PEX5L PHYH PRMT6
Entrez ID		38	5191
HPRD ID		01946	03454
Ensembl ID		ENSG00000075239	ENSG00000112357
Uniprot IDs		A0A140VJX1 A0A5F9ZHJ0 P24752	O00628 Q6FGN1
PDB IDs		2F2S 2IB7 2IB8 2IB9 2IBU 2IBW 2IBY
Enriched GO Terms of Interacting Partners?
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