KCNQ2 and KCNQ3

Data Source:
HPRD (in vivo)

		KCNQ2	KCNQ3
Description		potassium voltage-gated channel subfamily Q member 2	potassium voltage-gated channel subfamily Q member 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Node Of Ranvier Axon Initial Segment Synapse	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Node Of Ranvier Axon Initial Segment Synapse
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Ankyrin Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Chemical Synaptic Transmission Nervous System Development Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport	Chemical Synaptic Transmission Regulation Of Ion Transmembrane Transport Membrane Hyperpolarization Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels Interaction between L1 and Ankyrins	Voltage gated Potassium channels Interaction between L1 and Ankyrins
Drugs		Enflurane Amitriptyline Meclofenamic acid Promethazine Miconazole Ezogabine ICA-105665	Enflurane Amitriptyline Meclofenamic acid Gabapentin Promethazine Miconazole Ezogabine ICA-105665
Diseases		Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Perceived intensity of neohesperidin dihydrochalcone ( 31005972)	Coronary artery calcification ( 23870195) Height ( 28552196) LDL peak particle diameter (total fat intake interaction) ( 26112879) QT interval ( 29213071) Type 2 diabetes ( 31324766)
Interacting Genes		6 interacting genes: ARIH2 CALM1 CALM2 CALM3 KCNQ3 PRKCA	6 interacting genes: CALM1 CALM2 CALM3 KCNQ2 KCNQ4 KCNQ5
Entrez ID		3785	3786
HPRD ID		03757	09077
Ensembl ID		ENSG00000075043	ENSG00000184156
Uniprot IDs		O43526 Q53Y30	O43525
PDB IDs		5J03 6FEG 6FEH 7CR0 7CR1 7CR2 7CR3 7CR4 7CR7	5J03
Enriched GO Terms of Interacting Partners?
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